The College hostel, which started accommodating students since 1939, however, remained only for Muslims. It was only after 1947, that the hostel opened its doors to students from all communities.

Classes for Intermediate Arts started in July 1939 with 35 Muslim girls. Miss F.E. Grose was appointed Principal. There were only 9 faculty members: Miss Jean Mc Fayden (Prof. of English), Miss Shamsun Nahar Mahmud (Prof. of Bengali), Miss Fatema Begum (Lecturer in Urdu), Mr. Reza Ali Wahshat (Prof. of Persian), Maulana Abdul Khalique (Prof. of Arabic), Dr. Roma Chaudhuri (Prof. of Logic and Philosophy), Mrs. Bina Ghosh (Prof. of History), Mrs. Snigdhaprabha Mitra (Prof. of Mathematics), and Miss Kamala Sen (Lecturer in Civics and Economics). Mrs. Sabera Taib was the Librarian.

Members of the Governing Body included Begum Hamida Momem, MLC, Mrs. Fara Bano Khanum, MLA, Mrs. Hasina Murshed MLA  and MBE, (she was made Member of the British Empire by the then Emperor George VI on the recommendation of the Governor of Bengal, Sir John Woodhead), and Miss S.B. Gupta.

Affiliated to the University of Calcutta, the college at its inception began with teaching Urdu, Persian, Arabic, Bengali, English, History, Philosophy, Mathematics, and Economics __ as Optional and Pass Papers that were later extended to Honours level. Sanskrit, Chemistry, Physics and Geography were introduced in 1941, Zoology and Botany in 1950-51 and Political Science and Hindi in 1960. Lady Brabourne was first among the Government Colleges in West Bengal to start Sociology at the Undergraduate level when it was introduced as a Pass paper in 1988. It became an Honours course in 1994. The College was also the first women’s college that introduced Statistics as a Pass/General Paper in the year 2000. While the department of Microbiology was established in 2002, Statistics was elevated as an Honours department in 2005.

From being an exclusively Undergraduate college until 2002, the institution began extending into Post Graduate Courses (P.G.) and Ph.D. programmes with the Geography Department launching its P.G. Course in 2003. The Microbiology and Mathematics Departments followed suit in 2005 and 2006 respectively. The Physics and the English Departments began their P.G. Courses in 2007 and 2009 respectively. The Department of Bengali launched its P.G. Course in 2014. Each of these Post Graduate Departments now has an Advanced Research Centre, approved by the University of Calcutta. Four new P.G. Courses have been launched in 2016 by the Departments of Botany, Chemistry, Zoology and Political Science.

Today, Lady Brabourne College has 96 faculty members, 19 Undergraduate Honours and 2 exclusively Undergraduate Pass Courses (later called General, and now Generic Elective) namely, Computer Science and Women’s Studies. There are 10 Post Graduate Courses, besides various UGC sponsored Diploma and Certificate Courses.

The first institution to be established for the education of Muslim women, it has subsequently emerged as a multicultural venue for students from all over the country and from abroad. Today the College is a premier institution and a distinguished women’s college in West Bengal. Its cosmopolitan character and its emphasis on holistic development have contributed to the College attaining a unique position in the sphere of women’s education.